| 2025 | Twist | BookPage Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2025 | Twist | Kirkus Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2025 | Twist | Library Journal Best Books source ↗ (opens in a new tab) | Selection · Fiction | |
| 2025 | Twist | Publishers Weekly Best Books source ↗ (opens in a new tab) | Selection · Fiction | |
| 2025 | Twist: A Novel | Chicago Public Library Best of the Best source ↗ (opens in a new tab) | Selection · Must-Read Books: Fiction | |
| 2024 | American Mother | Kirkus Best Books of the Year source ↗ (opens in a new tab) | Selection · Nonfiction | |
| 2021 | Apeirogon | Dublin Literary Award source ↗ (opens in a new tab) | Shortlist · Fiction | |
| 2021 | Apeirogon | The Orwell Prize (book prizes) source ↗ (opens in a new tab) | Shortlist · Political Fiction | |
| 2021 | Apeirogon | Andrew Carnegie Medals for Excellence source ↗ (opens in a new tab) | Longlist · Fiction | |
| 2020 | Apeirogon | National Jewish Book Awards source ↗ (opens in a new tab) | Winner · Fiction | |
| 2020 | Apeirogon | Booker Prize source ↗ (opens in a new tab) | Longlist · Fiction | |
| 2020 | Apeirogon: A Novel | New York Public Library Best Books source ↗ (opens in a new tab) | Selection · Best Books for Adults | |
| 2020 | Apeirogon | The Irish Times Best Books of the Year source ↗ (opens in a new tab) | Selection · Books of the Year | |
| 2020 | Apeirogon | Library Journal Best Books source ↗ (opens in a new tab) | Selection · Literary Fiction | |
| 2016 | Thirteen Ways of Looking | The Story Prize source ↗ (opens in a new tab) | Finalist · Short Story Collection | |
| 2015 | TransAtlantic | Dublin Literary Award source ↗ (opens in a new tab) | Shortlist · Fiction | |
| 2015 | Thirteen Ways of Looking | Chicago Tribune Best Books of the Year source ↗ (opens in a new tab) | Selection · Best Books | |
| 2015 | Thirteen Ways Of Looking: Fiction | NPR Books We Love source ↗ (opens in a new tab) | Selection · Books We Love | |
| 2015 | Thirteen Ways of Looking | The Irish Times Best Books of the Year source ↗ (opens in a new tab) | Selection · Books of the Year | |
| 2015 | Thirteen Ways of Looking | The Boston Globe Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2015 | Thirteen Ways of Looking | New York Times 100 Notable Books source ↗ (opens in a new tab) | Selection · Fiction & Poetry | |
| 2013 | TransAtlantic | Booker Prize source ↗ (opens in a new tab) | Longlist · Fiction | |
| 2013 | TransAtlantic | Goodreads Choice Awards source ↗ (opens in a new tab) | Nominee · Historical Fiction | |
| 2013 | TransAtlantic | The Globe and Mail Globe 100 source ↗ (opens in a new tab) | Selection · Fiction | |
| 2013 | Transatlantic | Kirkus Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2013 | TransAtlantic | Paste Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2011 | Let the Great World Spin | Dublin Literary Award source ↗ (opens in a new tab) | Winner · Fiction | |
| 2009 | Let the Great World Spin | National Book Awards source ↗ (opens in a new tab) | Winner · Fiction | |
| 2009 | Let the Great World Spin | Booklist Editors' Choice source ↗ (opens in a new tab) | Selection · Adult Books: Fiction | |
| 2009 | Let the Great World Spin | Financial Times Best Books of the Year source ↗ (opens in a new tab) | Selection · Fiction | |
| 2009 | Let the Great World Spin | Entertainment Weekly Best Books source ↗ (opens in a new tab) | Selection · Fiction | |
| 2009 | Let the Great World Spin | New York Times 100 Notable Books source ↗ (opens in a new tab) | Selection · Fiction & Poetry | |
| 2009 | Let the Great World Spin | Amazon Editors' Best Books of the Year source ↗ (opens in a new tab) | Selection · Top 100 | |
| 2008 | Zoli | Dublin Literary Award source ↗ (opens in a new tab) | Longlist · Fiction | |
| 2007 | Zoli | Washington Post Best Books of the Year source ↗ (opens in a new tab) | Selection · Notable Fiction | |