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- 1All That She Carried: The Journey of Ashley’s Sack, a Black Family KeepsakeTiya Miles · 2021 · 2 honors
- 2On JuneteenthAnnette Gordon-Reed · 2021 · 2 honors
- 3The Copenhagen Trilogy: Childhood – Youth – DependencyTove Ditlevsen · 2021 · 2 honors
- 4A Fatal Thing Happened on the Way to the Forum: Murder in Ancient RomeEmma Southon · 2021 · 1 honor
- 5A Ghost in the ThroatDoireann Ní Ghríofa · 2021 · 1 honor
- 6A Most Remarkable Creature: The Hidden Life and Epic Journey of the World's Smartest Birds of PreyJonathan Meiburg · 2021 · 1 honor
- 7A Singing Army: Zilphia Horton and the Highlander Folk SchoolKim Ruehl · 2021 · 1 honor
- 8Aftershocks: A MemoirNadia Owusu · 2021 · 1 honor
- 9Against White Feminism: Notes on DisruptionRafia Zakaria · 2021 · 1 honor
- 10American Baby: A Mother, a Child, and the Shadow History of AdoptionGabrielle Glaser · 2021 · 1 honor
- 11Amoralman: A True Story and Other LiesDerek DelGaudio · 2021 · 1 honor
- 12Appleseed: A NovelMatt Bell · 2021 · 1 honor
- 13Baking with Dorie: Sweet, Salty & SimpleDorie Greenspan · 2021 · 1 honor
- 14Beautiful Country: A MemoirQian Julie Wang · 2021 · 1 honor
- 15Better, Not Bitter: Living on Purpose in the Pursuit of Racial JusticeYusef Salaam · 2021 · 1 honor
- 16Broken Horses: A MemoirBrandi Carlile · 2021 · 1 honor
- 17Castaway Mountain: Love and Loss Among the Wastepickers of MumbaiSaumya Roy · 2021 · 1 honor
- 18Certain and Impossible EventsCandace Jane Opper · 2021 · 1 honor
- 19Chasing Me to My Grave: An Artist's Memoir of the Jim Crow SouthWinfred Rembert and Erin I. Kelly · 2021 · 1 honor
- 20Chetna's 30 Minute Indian: Quick and Easy Everyday MealsChetna Makan · 2021 · 1 honor
- 21Children Under Fire: An American CrisisJohn Woodrow Cox · 2021 · 1 honor
- 22Colorization: One Hundred Years of Black Films in a White WorldWil Haygood · 2021 · 1 honor
- 23Cook Real Hawai'iSheldon Simeon With Garrett Snyder · 2021 · 1 honor
- 24Cook This Book: Techniques That Teach & Recipes to RepeatMolly Baz · 2021 · 1 honor
- 25Craft in the Real World: Rethinking Fiction Writing and WorkshoppingMatthew Salesses · 2021 · 1 honor
- 26Crying in H Mart: A MemoirMichelle Zauner · 2021 · 1 honor
- 27Cultish: The Language of FanaticismAmanda Montell · 2021 · 1 honor
- 28Demystifying Disability: What to Know, What to Say, and How to be an AllyEmily Ladau · 2021 · 1 honor
- 29Driving While Brown: Sheriff Joe Arpaio Versus the Latino ResistanceTerry Greene Sterling and Jude Joffe-Block · 2021 · 1 honor
- 30Eat, Habibi, Eat!: Fresh Recipes for Modern Egyptian CookingShahir Massoud · 2021 · 1 honor
- 31Empire of Pain: The Secret History of the Sackler DynastyPatrick Radden Keefe · 2021 · 1 honor
- 32Facing the Mountain: A True Story of Japanese American Heroes in World War IIDaniel James Brown · 2021 · 1 honor
- 33Flight of the Diamond Smugglers: A Tale of Pigeons, Obsession, and Greed Along Coastal South AfricaMatthew Gavin Frank · 2021 · 1 honor
- 34Flying Blind: The 737 Max Tragedy and the Fall of BoeingPeter Robison · 2021 · 1 honor
- 35FolklornAngela Mi Young Hur · 2021 · 1 honor
- 36Four Lost Cities: A Secret History of the Urban AgeAnnalee Newitz · 2021 · 1 honor
- 37Fulfillment: Winning and Losing in One-Click AmericaAlec MacGillis · 2021 · 1 honor
- 38Fuzz: When Nature Breaks the LawMary Roach · 2021 · 1 honor
- 39Gay Bar: Why We Went OutJeremy Atherton Lin · 2021 · 1 honor
- 40Gentrifier: A MemoirAnne Elizabeth Moore · 2021 · 1 honor
- 41Halfway Home: Race, Punishment, and the Afterlife of Mass IncarcerationReuben Jonathan Miller · 2021 · 1 honor
- 42House of Sticks: A MemoirLy Tran · 2021 · 1 honor
- 43How the Word Is PassedClint Smith · 2021 · 1 honor
- 44Hummingbird Salamander: A NovelJeff VanderMeer · 2021 · 1 honor
- 45Hurts So Good: The Science and Culture of Pain on PurposeLeigh Cowart · 2021 · 1 honor
- 46I Alone Can Fix It: Donald J. Trump's Catastrophic Final YearCarol Leonnig and Philip Rucker · 2021 · 1 honor
- 47Invisible ChildAndrea Elliott · 2021 · 1 honor
- 48Invisible Child: Poverty, Survival & Hope in an American CityAndrea Elliott · 2021 · 1 honor
- 49Jew-ish: A Cookbook: Reinvented Recipes from a Modern MenschJake Cohen · 2021 · 1 honor
- 50Just as I Am: A MemoirCicely Tyson · 2021 · 1 honor
- 51Kennedy's Avenger: Assassination, Conspiracy, and the Forgotten Trial of Jack RubyDan Abrams and David Fisher · 2021 · 1 honor
- 52Landslide: The Final Days of the Trump PresidencyMichael Wolff · 2021 · 1 honor
- 53Last Best Hope: America in Crisis and RenewalGeorge Packer · 2021 · 1 honor
- 54Last Call: A True Story of Love, Lust, and Murder in Queer New YorkElon Green · 2021 · 1 honor
- 55Last Chance Texaco: Chronicles of an American TroubadourRickie Lee Jones · 2021 · 1 honor
- 56Let the Record Show: A Political History of ACT UP New York, 1987-1993Sarah Schulman · 2021 · 1 honor
- 57Let Them Lead: Unexpected Lessons in Leadership from America's Worst High School Hockey TeamJohn U. Bacon · 2021 · 1 honor
- 58Mike Nichols: A LifeMark Harris · 2021 · 1 honor
- 59Mother Grains: Recipes for the Grain RevolutionRoxana Jullapat · 2021 · 1 honor
- 60My Broken Language: A MemoirQuiara Alegría Hudes · 2021 · 1 honor
- 61Names for Light: A Family HistoryThirii Myo Kyaw Myint · 2021 · 1 honor
- 62Nonbinary: A MemoirGenesis P-Orridge · 2021 · 1 honor
- 63Pastoral Song: A Farmer's JourneyJames Rebanks · 2021 · 1 honor
- 64People Love Dead Jews: Reports from a Haunted PresentDara Horn · 2021 · 1 honor
- 65Pregnant Girl: A Story of Teen Motherhood, College, and Creating a Better Future for Young FamiliesNicole Lynn Lewis · 2021 · 1 honor
- 66Putting It Together: How Stephen Sondheim and I Created Sunday in the Park with GeorgeJames Lapine · 2021 · 1 honor
- 67Real Estate: A Living AutobiographyDeborah Levy · 2021 · 1 honor
- 68Red CometHeather Clark · 2021 · 1 honor
- 69Refugee High: Coming of Age in AmericaElly Fishman · 2021 · 1 honor
- 70Remember: The Science of Memory and the Art of ForgettingLisa Genova · 2021 · 1 honor
- 71Robert E. Lee and Me: A Southerner's Reckoning with the Myth of the Lost CauseTy Seidule · 2021 · 1 honor
- 72Rosaline Palmer Takes the CakeAlexis Hall · 2021 · 1 honor
- 73Seeing Ghosts: A MemoirKat Chow · 2021 · 1 honor
- 74Sellout: The Major-Label Feeding Frenzy That Swept Punk, Emo, and Hardcore (1994-2007)Dan Ozzi · 2021 · 1 honor
- 75Shaking the Gates of Hell: A Search for Family and Truth in the Wake of the Civil Rights RevolutionJohn Archibald · 2021 · 1 honor
- 76Shooting Midnight Cowboy: Art, Sex, Loneliness, Liberation, and the Making of a Dark ClassicGlenn Frankel · 2021 · 1 honor
- 77Singing Like Germans: Black Musicians in the Land of Bach, Beethoven, and BrahmsKira Thurman · 2021 · 1 honor
- 78Somebody's Daughter: A MemoirAshley Ford · 2021 · 1 honor
- 79Speak, Okinawa: A MemoirElizabeth Miki Brina · 2021 · 1 honor
- 80Sumac: Recipes and Stories From SyriaAnas Atassi · 2021 · 1 honor
- 81Taste Makers: Seven Immigrant Women Who Revolutionized Food in AmericaMayukh Sen · 2021 · 1 honor
- 82Taste: My Life Through FoodStanley Tucci · 2021 · 1 honor
- 83Tastes Like War: A MemoirGrace M. Cho · 2021 · 1 honor
- 84The Caesars Palace Coup: How a Billionaire Brawl Over the Famous Casino Exposed the Power and Greed of Wall StreetSujeet Indap and Max Frumes · 2021 · 1 honor
- 85The Confidence Men: How Two Prisoners of War Engineered the Most Remarkable Escape in HistoryMargalit Fox · 2021 · 1 honor
- 86The Cookie BibleRose Levy Beranbaum · 2021 · 1 honor
- 87The Crime Without a Name: Ethnocide and the Erasure of Culture in AmericaBarrett Holmes Pitner · 2021 · 1 honor
- 88The Cult of We: WeWork, Adam Neumann, and the Great Startup DelusionEliot Brown and Maureen Farrell · 2021 · 1 honor
- 89The Dawn of Everything: A New History of HumanityDavid Graeber and David Wengrow · 2021 · 1 honor
- 90The Debt Trap: How Student Loans Became a National CatastropheJosh Mitchell · 2021 · 1 honor
- 91The Family Roe: An American StoryJoshua Prager · 2021 · 1 honor
- 92The Free World: Art and Thought in the Cold WarLouis Menand · 2021 · 1 honor
- 93The Good Girls: An Ordinary KillingSonia Faleiro · 2021 · 1 honor
- 94The Great Dissenter: The Story of John Marshall Harlan, America's Judicial HeroPeter S. Canellos · 2021 · 1 honor
- 95The Grizzly in the Driveway: The Return of Bears to a Crowded American WestRobert Chaney · 2021 · 1 honor
- 96The Haunting of Alma Fielding: A True Ghost StoryKate Summerscale · 2021 · 1 honor
- 97The Isolation Artist: Scandal, Deception, and the Last Days of Robert IndianaBob Keyes · 2021 · 1 honor
- 98The Kissing Bug: A True Story of a Family, an Insect, and a Nation's Neglect of a Deadly DiseaseDaisy Hernández · 2021 · 1 honor
- 99The Light of Days: The Untold Story of Women Resistance Fighters in Hitler's GhettosJudy Batalion · 2021 · 1 honor
- 100The Loneliest AmericansJay Caspian Kang · 2021 · 1 honor
- 101The Mirror and the Palette: Rebellion, Revolution and Resilience: Five Hundred Years of Women's Self PortraitsJennifer Higgie · 2021 · 1 honor
- 102The Natural Mother of the Child: A Memoir of Nonbinary ParenthoodKrys Malcom Belc · 2021 · 1 honor
- 103The Price You Pay for College: An Entirely New Road Map for the Biggest Financial Decision Your Family Will Ever MakeRob Lieber · 2021 · 1 honor
- 104The Prisoner: A MemoirHwang Sok-yong, translated by Sora Kim-Russell and Anton Hur · 2021 · 1 honor
- 105The Red Boat Fish Sauce Cook Book: Beloved Recipes from the Family Behind the Purest Fish SauceCuong Pham with Tien Nguyen and Diep Tran · 2021 · 1 honor
- 106The Secret History of Home Economics: How Trailblazing Women Harnessed the Power of Home and Changed the Way We LiveDanielle Dreilinger · 2021 · 1 honor
- 107The Secret of Life: Rosalind Franklin, James Watson, Francis Crick, and the Discovery of DNA’s Double HelixHoward Markel · 2021 · 1 honor
- 108The State Must Provide: Why America's Colleges Have Always Been Unequal – And How to Set Them RightAdam Harris · 2021 · 1 honor
- 109The Third Pole: Mystery, Obsession, and Death on Mount EverestMark Synnott · 2021 · 1 honor
- 110The Three Mothers: How the Mothers of Martin Luther King, Jr., Malcolm X, and James Baldwin Shaped a NationAnna Malaika Tubbs · 2021 · 1 honor
- 111The Twisted Soul Cookbook: Modern Soul Food with Global FlavorsDeborah VanTrece · 2021 · 1 honor
- 112The Whiteness of Wealth: How the Tax System Impoverishes Black Americans – And How We Can Fix ItDorothy A. Brown · 2021 · 1 honor
- 113This is Your Mind on PlantsMichael Pollan · 2021 · 1 honor
- 114Under a White Sky: The Nature of the FutureElizabeth Kolbert · 2021 · 1 honor
- 115Until Justice Be Done: America's First Civil Rights Movement, from the Revolution to ReconstructionKate Masur · 2021 · 1 honor
- 116Until Proven Safe: The History and Future of QuarantineGeoff Manaugh and Nicola Twilley · 2021 · 1 honor
- 117Want Me: A Sex Writer's Journey Into the Heart of DesireTracy Clark-Flory · 2021 · 1 honor
- 118We Are Bridges: A MemoirCassandra Lane · 2021 · 1 honor
- 119We Had a Little Real Estate Problem: The Unheralded Story of Native Americans & ComedyKliph Nesteroff · 2021 · 1 honor
- 120When Evil Lived in Laurel: The "White Knights" and the Murder of Vernon DahmerCurtis Wilkie · 2021 · 1 honor
- 121White Freedom: The Racial History of an IdeaTyler Stovall · 2021 · 1 honor
- 122Wilmington’s Lie: The Murderous Coup of 1898 and the Rise of White SupremacyDavid Zucchino · 2021 · 1 honor